1113025-86-7
1113025-86-7
Chemical Structure
LB-205
- CAS No.: 1113025-86-7
- Formula:C19H22N2O2S
- Molecular Weight:342.46
IUPAC Name: 2-mercapto-N-(6-oxo-6-(phenylamino)hexyl)benzamide
InChIKey: DLAHPFVJAZCDGF-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1S)NCCCCCC(NC2=CC=CC=C2)=O
Biological Activity: LB-205 is a pan-histone deacetylase inhibitor (HDACi). LB-205 can be used for the research of acute traumatic brain injury[1][2].
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LB-205 | LB-205 is a pan-histone deacetylase inhibitor (HDACi). LB-205 can be used for the research of acute traumatic brain injury. | |||||||||||||||||||||
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References
- [1]. Lu J, et, al. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52. [Content Brief]
- [2]. Lu J, et, al. Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5. [Content Brief]
Keywords
