111988-19-3
Chemical Structure
Octopamine-d3
Synonym(s): (±)-p-Octopamine-d3
- CAS No.: 111988-19-3
- Formula:C8H8D3NO2
- Molecular Weight:156.20
IUPAC Name: N-methyl-N-(methyl-d3)-2-(phenyl(o-tolyl)methoxy)ethan-1-amine
InChIKey: QHGUCRYDKWKLMG-VWTWQGAWSA-N
SMILES: NC([2H])([2H])C(C1=CC=C(C=C1)O)([2H])O
Biological Activity: Octopamine-d3 ((±)-p-Octopamine-d3) is the deuterated-labeled Octopamine (HY-B0528). Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases[1][2][3][4].
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Octopamine-d3 | 99.52% | Octopamine-d3 ((±)-p-Octopamine-d3) is the deuterated-labeled Octopamine (HY-B0528). Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases. | ||||||||||||||||||||
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Octopamine | 99.93% | Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases. | ||||||||||||||||||||
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References
- [1]. Axelrod J, et al. Octopamine. Nature. 1977 Feb 10;265(5594):501-4. [Content Brief]
- [2]. Kaya-Zeeb S, et al. Octopamine drives honeybee thermogenesis. eLife. 2022 Mar 15;11:e74334.
- [3]. Farooqui T, et al. Octopamine-mediated neuromodulation of insect senses. Neurochemical research. 2007 Sep;32(9):1511-29. [Content Brief]
- [4]. Selcho M, et al. Linking physiological processes and feeding behaviors by octopamine. Current opinion in insect science. 2019 Dec;36:125-130.
