113243-75-7
Chemical Structure
FR 76830
- CAS No.: 113243-75-7
- Formula:C25H26N4O4
- Molecular Weight:446.50
IUPAC Name: 2-methyl-N-(2-morpholinoethyl)-4-(3-nitrophenyl)-6-phenylnicotinamide
InChIKey: HNBRMVZTOLAZRW-UHFFFAOYSA-N
SMILES: O=C(NCCN1CCOCC1)C2=C(C)N=C(C3=CC=CC=C3)C=C2C4=CC=CC([N+]([O-])=O)=C4
Biological Activity: FR 76830 is a bradycardic agent with cardiomyocyte protective effects. FR 76830 attenuates the decrease in myocardial pH during the early stage of ischemia. FR 76830 improves ATP levels during the late stage of ischemia. FR 76830 reduces heart rate in a dose-dependent manner without decreasing the rate-pressure product of the myocardium. FR 76830 exerts cardioprotective effects during ischemia and reperfusion. FR 76830 can be used for the research of myocardial ischemia-reperfusion injury[1].
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FR 76830 | FR 76830 is a bradycardic agent with cardiomyocyte protective effects. FR 76830 attenuates the decrease in myocardial pH during the early stage of ischemia. FR 76830 improves ATP levels during the late stage of ischemia. FR 76830 reduces heart rate in a dose-dependent manner without decreasing the rate-pressure product of the myocardium. FR 76830 exerts cardioprotective effects during ischemia and reperfusion. FR 76830 can be used for the research of myocardial ischemia-reperfusion injury. | |||||||||||||||||||||
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