1135-99-5
Chemical Structure
NSC405640
- CAS No.: 1135-99-5
- Formula:C12H10Cl2Sn
- Molecular Weight:343.82
IUPAC Name: dichlorodiphenylstannane
InChIKey: ISXUHJXWYNONDI-UHFFFAOYSA-L
SMILES: Cl[Sn](C1=CC=CC=C1)(C2=CC=CC=C2)Cl
Biological Activity: NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53[1].
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NSC405640 | 98.0% | NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53. | ||||||||||||||||||||
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Diphenyltin Dichloride-d10 | Diphenyltin Dichloride-d10 is the deuterium labeled NSC405640 (HY-144105). NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53. | |||||||||||||||||||||
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Keywords