113639-01-3
113639-01-3
Chemical Structure
5-Aminolevulinic acid-13C2,15N hydrochloride
Synonym(s): 5-ALA-13C2,15N hydrochloride; δ-Aminolevulinic acid-13C2,15N hydrochloride; 5-Amino-4-oxopentanoic acid-13C2,15N hydrochloride
- CAS No.: 113639-01-3
- Formula:C313C2H10Cl15NO3
- Molecular Weight:170.57
IUPAC Name: 5-(amino-15N)-4-oxopentanoic-4,5-13C2 acid hydrochloride
InChIKey: ZLHFONARZHCSET-MBIZCHBVSA-N
SMILES: O=C(O)CC[13C]([13CH2][15NH2])=O.Cl
Biological Activity: 5-Aminolevulinic acid-13C2,15N (5-ALA-13C2,15N; δ-Aminolevulinic acid-13C2,15N) is 13C- and 15N-labeled 5-Aminolevulinic acid (HY-W000450)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Aminolevulinic acid-13C2,15N hydrochloride | 99.94% | 5-Aminolevulinic acid-13C2,15N (5-ALA-13C2,15N; δ-Aminolevulinic acid-13C2,15N) is 13C- and 15N-labeled 5-Aminolevulinic acid (HY-W000450). | ||||||||||||||||||||
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5-Aminolevulinic acid-13C | 5-Aminolevulinic acid-13C is the 13C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis. | |||||||||||||||||||||
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5-Aminolevulinic acid | 99.92% | 5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy. | ||||||||||||||||||||
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References
