1136466-93-7
Chemical Structure
IDE 2
- CAS No.: 1136466-93-7
- Formula:C12H20N2O3
- Molecular Weight:240.30
IUPAC Name: 7-(2-cyclopentylidenehydrazinyl)-7-oxoheptanoic acid
InChIKey: CVYPYYPTFNVREL-UHFFFAOYSA-N
SMILES: O=C(CCCCCC(O)=O)N/N=C1CCCC/1
Biological Activity: IDE 2 is a cell-permeable inducer of definitive endoderm differentiation that induces the differentiation of mouse and human embryonic stem cells into definitive endoderm. IDE2 activates the TGF‑β/Nodal signaling pathway, induces Smad2 phosphorylation, and increases Sox17 and FoxA2 expression. Endoderm induced by IDE 2 integrates into the developing gut tube, expresses gut tube markers, and differentiates into pancreatic progenitor cells. IDE 2 can be used for research related to directed endoderm differentiation of embryonic stem cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IDE 2 | 99.0% | IDE 2 is a cell-permeable inducer of definitive endoderm differentiation that induces the differentiation of mouse and human embryonic stem cells into definitive endoderm. IDE2 activates the TGF‑β/Nodal signaling pathway, induces Smad2 phosphorylation, and increases Sox17 and FoxA2 expression. Endoderm induced by IDE 2 integrates into the developing gut tube, expresses gut tube markers, and differentiates into pancreatic progenitor cells. IDE 2 can be used for research related to directed endoderm differentiation of embryonic stem cells. | ||||||||||||||||||||
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