113886-72-9
113886-72-9
Chemical Structure
2’-O-Methyl-2-thiouridine
- CAS No.: 113886-72-9
- Formula:C10H14N2O5S
- Molecular Weight:274.29
IUPAC Name: 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: WARUUAMZJXEUEA-ZOQUXTDFSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=S)O1
Biological Activity: 2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-O-Methyl-2-thiouridine | 2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
