114547-31-8
114547-31-8
Chemical Structure
Galanin (1-29)(rat, mouse)
- CAS No.: 114547-31-8
- Formula:C141H211N43O41
- Molecular Weight:3164.45
SMILES: [GWTLNSAGYLLGPHAIDNHRSFSDKHGLT-NH2]
Biological Activity: Galanin (1-29)(rat, mouse) is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively. Anticonvulsant effect[1][2].
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Galanin (1-29)(rat, mouse) | Galanin (1-29)(rat, mouse) is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively. Anticonvulsant effect. | |||||||||||||||||||||
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References
- [1]. Wang S, et al. Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J Biol Chem. 1997;272(51):31949-31952. [Content Brief]
- [2]. Mazarati A, et al. Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: The effects of subtype-selective agonists and the role of G-protein-mediated signaling. J Pharmacol Exp Ther. 2006;318(2):700-708. [Content Brief]
