114776-28-2
Chemical Structure
Bepafant
Synonym(s): Web2170
- CAS No.: 114776-28-2
- Formula:C23H22ClN5O2S
- Molecular Weight:467.97
IUPAC Name: (6-(2-chlorophenyl)-1-methyl-8,9-dihydro-4H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-8-yl)(morpholino)methanone
InChIKey: FWYVRZOREBYLCY-UHFFFAOYSA-N
SMILES: O=C(C1CC2=C(C1)C(C(C3=C(Cl)C=CC=C3)=NCC4=NN=C(C)N45)=C5S2)N6CCOCC6
Biological Activity: Bepafant (Web2170) is a platelet-activating factor (PAF) antagonist that protects against anaphylactic lethality in active and passive anaphylaxis models in mice and guinea pigs in a dose-dependent manner and attenuates bronchoconstriction and blood pressure changes in anaphylaxis.
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Bepafant | Bepafant (Web2170) is a platelet-activating factor (PAF) antagonist that protects against anaphylactic lethality in active and passive anaphylaxis models in mice and guinea pigs in a dose-dependent manner and attenuates bronchoconstriction and blood pressure changes in anaphylaxis. | |||||||||||||||||||||
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Keywords
