115993-88-9
Chemical Structure
8-NBD-cGMP
- CAS. Nr.: 115993-88-9
- Formula:C18H18N9O10PS
- Molecular Weight:583.43
IUPAC Name: 2-amino-9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-8-((2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)thio)-1,9-dihydro-6H-purin-6-one
InChIKey: OFZLFLCFZIWIFU-KWDXPJCYSA-N
SMILES: O=C1C(N=C(SCCNC2=CC=C([N+]([O-])=O)C3=NON=C32)N4[C@H]5[C@H](O)[C@H](O6)[C@@H](COP6(O)=O)O5)=C4N=C(N)N1
Biological Activity: 8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1]
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8-NBD-cGMP | 8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites | |||||||||||||||||||||
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