1159997-27-9
1159997-27-9
Chemical Structure
AMG9678
- CAS No.: 1159997-27-9
- Formula:C20H18F6N2O
- Molecular Weight:416.36
IUPAC Name: (R)-1-(4-(trifluoromethyl)phenyl)-N-((S)-1,1,1-trifluoropropan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
InChIKey: OGMWZDQYXGKSBP-YVEFUNNKSA-N
SMILES: O=C(N1CCC2=C(C=CC=C2)[C@H]1C3=CC=C(C(F)(F)F)C=C3)N[C@@H](C)C(F)(F)F
Biological Activity: AMG9678 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 31.2 nM[1].
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AMG9678 | AMG9678 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 31.2 nM. | |||||||||||||||||||||
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References
Keywords
