1160589-73-0
1160589-73-0
Chemical Structure
CHS-828 (nicotinate)
Synonym(s): GMX1778 (nicotinate)
- CAS No.: 1160589-73-0
- Formula:C25H27ClN6O3
- Molecular Weight:494.97
SMILES: N#CN/C(NCCCCCCOC1=CC=C(C=C1)Cl)=N\C2=CC=NC=C2.O=C(C3=CC=CN=C3)O
Biological Activity: CHS-828 nicotinate is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 nicotinate (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1].
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CHS-828 (nicotinate) | CHS-828 nicotinate is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 nicotinate (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity. | |||||||||||||||||||||
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References
Keywords
