1162665-52-2
1162665-52-2
Chemical Structure
IDX375
- CAS No.: 1162665-52-2
- Formula:C24H37N4O6PS
- Molecular Weight:540.61
IUPAC Name: N-((S)-3-((S)-5-(tert-butyl)-1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-1-ethoxy-1-oxido-4H-benzo[c][1,5,2]diazaphosphinin-7-yl)methanesulfonamide
InChIKey: FKLYVKZFUGOUQH-GOKJBEJGSA-N
SMILES: CS(=O)(NC1=CC=C(C2=C1)NC(C3=C(O)[C@H](C(C)(C)C)N(CCC(C)(C)C)C3=O)=N[P@]2(OCC)=O)=O
Biological Activity: IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1].
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IDX375 | IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies. | |||||||||||||||||||||
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