1164469-60-6
Chemical Structure
Naftopidil hydrochloride
Synonym(s): KT-611 hydrochloride; BM-15275 hydrochloride
- CAS No.: 1164469-60-6
- Formula:C24H29ClN2O3
- Molecular Weight:428.95
IUPAC Name: 1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
InChIKey: VQAAEWMEVIOHTJ-UHFFFAOYSA-N
SMILES: [H]Cl.OC(CN1CCN(C(C=CC=C2)=C2OC)CC1)COC3=CC=CC4=CC=CC=C34
Biological Activity: Naftopidil hydrochloride (KT-611 hydrochloride) is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil hydrochloride has antiproliferative effects. Naftopidil hydrochloride can be used for the research of prostate hyperplasia[1].
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Naftopidil hydrochloride | 99.97% | Naftopidil hydrochloride (KT-611 hydrochloride) is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil hydrochloride has antiproliferative effects. Naftopidil hydrochloride can be used for the research of prostate hyperplasia. | ||||||||||||||||||||
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Keywords
