1185061-66-8
1185061-66-8
Chemical Structure
NRAS-G4-ligand-1
- CAS No.: 1185061-66-8
- Formula:C25H22N6O3S
- Molecular Weight:486.55
InChIKey: BMVZCTKXPMDBBP-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(CCNC2=C3C(C=CC=C3)=NC(C4=NN=C(O4)C5=CC=C(C=C5)C)=N2)C=C1)(N)=O
Biological Activity: NRAS-G4-ligand-1 is a NRAS-G4 binder with Kd values of 0.25 μM (AlexaFluor 647-labeled) and 0.932 μM (biotinylated), respectively. NRAS-G4-ligand-1 acts as a translation inhibitor, reduces cancer cell viability, and downregulates NRAS protein levels. NRAS-G4-ligand-1 can be used in the research of melanoma and breast cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NRAS-G4-ligand-1 | 90.0% | NRAS-G4-ligand-1 is a NRAS-G4 binder with Kd values of 0.25 μM (AlexaFluor 647-labeled) and 0.932 μM (biotinylated), respectively. NRAS-G4-ligand-1 acts as a translation inhibitor, reduces cancer cell viability, and downregulates NRAS protein levels. NRAS-G4-ligand-1 can be used in the research of melanoma and breast cancer. | ||||||||||||||||||||
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