1185242-27-6
1185242-27-6
Chemical Structure
Cinnarizine-d8
- CAS No.: 1185242-27-6
- Formula:C26H20D8N2
- Molecular Weight:376.56
IUPAC Name: 1-benzhydryl-4-cinnamylpiperazine-2,2,3,3,5,5,6,6-d8
InChIKey: DERZBLKQOCDDDZ-RVEWZOGKSA-N
SMILES: [2H]C1([2H])C([2H])([2H])N(C/C=C/C2=CC=CC=C2)C([2H])([2H])C([2H])([2H])N1C(C3=CC=CC=C3)C4=CC=CC=C4
Biological Activity: Cinnarizine-d8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.
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Cinnarizine-d8 | 98.24% | Cinnarizine-d8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker. | ||||||||||||||||||||
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Cinnarizine (Standard) | 99.01% | Cinnarizine (Standard) is the analytical standard of Cinnarizine. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Cinnarizine | 99.56% | Cinnarizine is an orally active, effective and selective inhibitor of L-type calcium channel Cav1.3 with an IC50 of 1.5 μM (in vestibular hair cells). Cinnarizine can cross the blood-brain barrier and regulate calcium homeostasis and dopamine neurotransmission. Cinnarizine inhibits the influx of calcium ions into smooth muscle cells by blocking L-type calcium channels, thereby relaxing vascular smooth muscle, improving cerebral circulation and reducing blood viscosity, while antagonizing dopamine receptors. Cinnarizine can be used in the study of vestibular vertigo, Meniere's disease and cerebrovascular diseases. | ||||||||||||||||||||
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