1189488-17-2
1189488-17-2
Chemical Structure
N-Desmethyl-loperamide-d3
- CAS No.: 1189488-17-2
- Formula:C28H28D3ClN2O2
- Molecular Weight:466.03
IUPAC Name: 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-(methyl-d3)-2,2-diphenylbutanamide
InChIKey: ZMOPTLXEYOVARP-FIBGUPNXSA-N
SMILES: OC(CC1)(C2=CC=C(C=C2)Cl)CCN1CCC(C3=CC=CC=C3)(C4=CC=CC=C4)C(NC([2H])([2H])[2H])=O
Biological Activity: N-Desmethyl-loperamide-d3 is the deuterium labeled N-Desmethyl-loperamide[1].
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N-Desmethyl-loperamide-d3 | N-Desmethyl-loperamide-d3 is the deuterium labeled N-Desmethyl-loperamide. | |||||||||||||||||||||
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N-Desmethyl-loperamide | 98.36% | N-Desmethyl-loperamide is a major metabolite of loperamide, a drug that selectively activates peripheral μopioid receptors with a Ki value of 0.16 nM. N-Desmethyl-loperamide is a substrate of the ATP-dependent efflux transporter P-glycoprotein. | ||||||||||||||||||||
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References
