119515-00-3
119515-00-3
Chemical Structure
CysLT1 receptor antagonist-1
- CAS No.: 119515-00-3
- Formula:C18H15NO3
- Molecular Weight:293.32
InChIKey: INKCQRGAPBDVIZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1)OC
Biological Activity: CysLT1 receptor antagonist-1 (Compound 4) is an antagonist for cysteinyl leukotriene receptor 1 (CysLT1R) with an IC50 of 3.9 μM. CysLT1 receptor antagonist-1 exhibits weak agonist activity against G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficact of 23% at 10 μM. CysLT1 receptor antagonist-1 can be used for asthma and allergic diseases researchs[1].
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CysLT1 receptor antagonist-1 | CysLT1 receptor antagonist-1 (Compound 4) is an antagonist for cysteinyl leukotriene receptor 1 (CysLT1R) with an IC50 of 3.9 μM. CysLT1 receptor antagonist-1 exhibits weak agonist activity against G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficact of 23% at 10 μM. CysLT1 receptor antagonist-1 can be used for asthma and allergic diseases researchs. | |||||||||||||||||||||
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References
Keywords
