120191-51-7
120191-51-7
Chemical Structure
Streptochlorin
Synonym(s): SF2583A
- CAS. Nr.: 120191-51-7
- Formula:C11H7ClN2O
- Molecular Weight:218.64
IUPAC Name: 4-chloro-5-(1H-indol-3-yl)oxazole
InChIKey: BKYJGKRXUHPPLR-UHFFFAOYSA-N
SMILES: ClC1=C(C2=CNC3=C2C=CC=C3)OC=N1
Biological Activity: Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1[1][2].
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Streptochlorin | Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1. | |||||||||||||||||||||
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References
- [1]. Shin DY, et, al. Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. J Microbiol Biotechnol. 2008 Nov;18(11):1862-8. [Content Brief]
- [2]. Iwatsuki M, et, al. In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships. J Antibiot (Tokyo). 2010 Oct;63(10):619-22. [Content Brief]
