120205-58-5
120205-58-5
Chemical Structure
Monomethyl auristatin E intermediate-9
- CAS No.: 120205-58-5
- Formula:C22H35NO5
- Molecular Weight:393.52
IUPAC Name: tert-butyl (3R,4S,5S)-4-(((benzyloxy)carbonyl)(methyl)amino)-3-methoxy-5-methylheptanoate
InChIKey: PCUHBNWYHLQSBO-HQRMLTQVSA-N
SMILES: CC[C@H](C)[C@@H]([C@@H](CC(OC(C)(C)C)=O)OC)N(C(OCC1=CC=CC=C1)=O)C
Biological Activity: Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-9 | Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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References
