122299-14-3
122299-14-3
Chemical Structure
Eglin c (60-63)
- CAS No.: 122299-14-3
- Formula:C18H33N5O7
- Molecular Weight:431.48
InChIKey: KAMOTFUFDACEHJ-ZZEGJQGJSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@H](N)[C@H](O)C)=O)=O)=O
Biological Activity: Eglin c (60-63) is a selective Elastase inhibitor, with a Ki value of 2.3e-3 M against human leukocyte hElastase and a Ki value of 4.8e-3 M against porcine pancreatic Elastase. Eglin c (60-63) can be used in research related to rheumatoid arthritis[1].
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Eglin c (60-63) | Eglin c (60-63) is a selective Elastase inhibitor, with a Ki value of 2.3e-3 M against human leukocyte hElastase and a Ki value of 4.8e-3 M against porcine pancreatic Elastase. Eglin c (60-63) can be used in research related to rheumatoid arthritis. | |||||||||||||||||||||
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References
- [1]. Tsuboi S, et al. Amino acids and peptides. XXX. Synthesis of eglin c (41-49) and eglin c (60-63) and examination of their inhibitory activity towards human leukocyte elastase, cathepsin G, porcine pancreatic elastase and alpha-chymotrypsin. Chem Pharm Bull (Tokyo). 1991 Jan;39(1):184-6. [Content Brief]
Keywords
