1225383-38-9
Chemical Structure
PROTAC CRABP-II Degrader-2
- CAS No.: 1225383-38-9
- Formula:C44H64N4O10
- Molecular Weight:809.00
IUPAC Name: (2E,4E,6E,8E)-9-((E)-3-((((14S,17S,18R)-18-amino-17-hydroxy-14-isobutyl-2,13,16-trioxo-19-phenyl-6,9,12-trioxa-3,15-diazanonadecyl)oxy)imino)-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
InChIKey: LJDTZKKSXVIAPQ-FATAJGLMSA-N
SMILES: CC(/C=C/C=C(/C=C/C1=C(/C(CCC(C)1C)=N/OCC(NCCOCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC2=CC=CC=C2)=O)=O)=O)C)C)=C\C(O)=O
Biological Activity: PROTAC CRABP-II Degrader-2 is a cellular retinoic acid-binding protein (CRABP-II) SNIPER degrader. PROTAC CRABP-II Degrader-2 hijacks the cIAP1 E3 ligase to induce ubiquitination and proteasomal degradation of CRABP-II. PROTAC CRABP-II Degrader-2 can be used for the research of neuroblastoma[1].
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PROTAC CRABP-II Degrader-2 | PROTAC CRABP-II Degrader-2 is a cellular retinoic acid-binding protein (CRABP-II) SNIPER degrader. PROTAC CRABP-II Degrader-2 hijacks the cIAP1 E3 ligase to induce ubiquitination and proteasomal degradation of CRABP-II. PROTAC CRABP-II Degrader-2 can be used for the research of neuroblastoma. | |||||||||||||||||||||
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Keywords
