1228182-50-0
1228182-50-0
Chemical Structure
Baquiloprim-d6
- CAS No.: 1228182-50-0
- Formula:C17H14D6N6
- Molecular Weight:314.42
IUPAC Name: 5-((8-(bis(methyl-d3)amino)-7-methylquinolin-5-yl)methyl)pyrimidine-2,4-diamine
InChIKey: AIOWJIMWVFWROP-XERRXZQWSA-N
SMILES: [2H]C([2H])([2H])N(C([2H])([2H])[2H])C(C(N=CC=C1)=C1C(CC2=CN=C(N)N=C2N)=C3)=C3C
Biological Activity: Baquiloprim-d6 is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].
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Baquiloprim-d6 | Baquiloprim-d6 is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria. | |||||||||||||||||||||
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Baquiloprim (Standard) | ≥98% | Baquiloprim (Standard) is the analytical standard of Baquiloprim. This product is intended for research and analytical applications. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria. | ||||||||||||||||||||
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Baquiloprim | 99.66% | Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Lewicki J, et, al. Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res Vet Sci. 1995 May;58(3):268-71. [Content Brief]
