122955-13-9
122955-13-9
Chemical Structure
XE991 dihydrochloride
- CAS No.: 122955-13-9
- Formula:C26H22Cl2N2O
- Molecular Weight:449.37
IUPAC Name: 10,10-bis(pyridin-4-ylmethyl)anthracen-9(10H)-one dihydrochloride
InChIKey: WOGWMARIFDNZON-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(CC3=CC=NC=C3)(CC4=CC=NC=C4)C5=CC=CC=C15.Cl.Cl
Biological Activity: XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XE991 dihydrochloride | XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. | |||||||||||||||||||||
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XE991 dihydrochloride (Standard) | ≥98% | XE991 dihydrochloride (Standard) is the analytical standard of XE991 dihydrochloride. This product is intended for research and analytical applications. XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. | ||||||||||||||||||||
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References
