1231-74-9
Chemical Structure
Methyl O-methylpodocarpate
- CAS No.: 1231-74-9
- Formula:C19H26O3
- Molecular Weight:302.41
IUPAC Name: methyl (1S,4aS,10aR)-6-methoxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate
InChIKey: BSKWXDWRTACMCC-QRQLOZEOSA-N
SMILES: C[C@@]12[C@]([C@](C(OC)=O)(C)CCC1)(CCC=3C2=CC(OC)=CC3)[H]
Biological Activity: Methyl O-methylpodocarpate is an influenza A virus (H1N1) inhibitor with activity against H1N1 strains resistant to Oseltamivir and Amantadine, with an EC50 of 0.73 μM. Methyl O-methylpodocarpate blocks viral membrane fusion by targeting hemagglutinin (HA). Methyl O-methylpodocarpate shows only weak activity against the H3N2 subtype and exhibits no significant cytotoxicity to MDCK cells. Methyl O-methylpodocarpate can be used in studies related to H1N1 infection[1].
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Methyl O-methylpodocarpate | Methyl O-methylpodocarpate is an influenza A virus (H1N1) inhibitor with activity against H1N1 strains resistant to Oseltamivir and Amantadine, with an EC50 of 0.73 μM. Methyl O-methylpodocarpate blocks viral membrane fusion by targeting hemagglutinin (HA). Methyl O-methylpodocarpate shows only weak activity against the H3N2 subtype and exhibits no significant cytotoxicity to MDCK cells. Methyl O-methylpodocarpate can be used in studies related to H1N1 infection. | |||||||||||||||||||||
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Keywords
