1234481-08-3
Chemical Structure
XMD-12
- CAS No.: 1234481-08-3
- Formula:C24H26N6O2
- Molecular Weight:430.50
IUPAC Name: 2-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
InChIKey: DFQAJLQXPSPNJE-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC=C2N(C)C3=NC(NC4=CC=C(N5CCC(O)CC5)C=C4)=NC=C3N1C
Biological Activity: XMD-12 (compound 1) is an Aurora kinase (Aurora Kinase) inhibitor with anti-tumor activity that promotes paclitaxel (HY-B0015) induced cell death. XMD-12 exhibits high selectivity and potency against Aurora A, B, and C kinases, with IC50 values of 5.6, 18.4, and 24.6 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XMD-12 | 99.32% | XMD-12 (compound 1) is an Aurora kinase (Aurora Kinase) inhibitor with anti-tumor activity that promotes paclitaxel (HY-B0015) induced cell death. XMD-12 exhibits high selectivity and potency against Aurora A, B, and C kinases, with IC50 values of 5.6, 18.4, and 24.6 nM, respectively. | ||||||||||||||||||||
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Keywords
