123882-89-3
Chemical Structure
RS-64459-193
- CAS No.: 123882-89-3
- Formula:C26H36Cl2N2O2
- Molecular Weight:479.48
IUPAC Name: 8-(4-(5-chloro-3,4,8,9,10,10a-hexahydronaphtho[1,8-cd]azepin-2(1H)-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride
InChIKey: LOCVDLICIHQFMB-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2(CCCC2)C1)=O)CCCCN3CC4C5=C(CCC4)C=CC(Cl)=C5CC3.[H]Cl
Biological Activity: RS-64459-193 is a 5-HT1A receptor partial agonist with a Ki of 24.9 nM. RS-64459-193 also shows high affinity for 5-HT2C, 5-HT2A and 5-HT7 with pKi values of 6.87, 7.02, and 7.18, respectively. RS-64459-193 is almost devoid of activity at the m 5-HT3 receptor[1].
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RS-64459-193 | RS-64459-193 is a 5-HT1A receptor partial agonist with a Ki of 24.9 nM. RS-64459-193 also shows high affinity for 5-HT2C, 5-HT2A and 5-HT7 with pKi values of 6.87, 7.02, and 7.18, respectively. RS-64459-193 is almost devoid of activity at the m 5-HT3 receptor. | |||||||||||||||||||||
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Keywords
