RS-64459-193
RS-64459-193 is a 5-HT1A receptor partial agonist with a Ki of 24.9 nM. RS-64459-193 also shows high affinity for 5-HT2C, 5-HT2A and 5-HT7 with pKi values of 6.87, 7.02, and 7.18, respectively. RS-64459-193 is almost devoid of activity at the m 5-HT3 receptor.
For research use only. We do not sell to patients.
- CAS No.: 123882-89-3
- Formula: C26H36Cl2N2O2
- Molecular Weight:479.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All 5-HT Receptor Isoforms
More
Biological Activity
|
5-HT1A Receptor |
5-HT2A Receptor |
5-HT2C Receptor |
5-HT7 Receptor |
5-HT1A Receptor 24.9 nM (Ki, CHO cells) |
human 5-HT1A Receptor 7.6 (pKi, Sf9) |
human 5-HT1A Receptor 7.04 (pKi) |
5-HT2C Receptor 6.87 (pKi) |
Rat 5-HT2A 7.02 (pKi) |
Human 5-HT7 Receptor 7.18 (pKi) |
5-HT3 Receptor <4 (pKi) |
Chemical Information
-
CAS No. 123882-89-3
-
Molecular Weight 479.48
-
Formula C26H36Cl2N2O2
-
SMILES
O=C1N(C(CC2(CCCC2)C1)=O)CCCCN3CC4C5=C(CCC4)C=CC(Cl)=C5CC3.[H]Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz