1239987-91-7
1239987-91-7
Chemical Structure
GPR52 antagonist-1
- CAS No.: 1239987-91-7
- Formula:C15H14OS
- Molecular Weight:242.34
IUPAC Name: (E)-5-phenyl-1-(thiophen-2-yl)pent-2-en-1-one
InChIKey: XUIAIACHIPOOHR-BJMVGYQFSA-N
SMILES: O=C(C1=CC=CS1)/C=C/CCC2=CC=CC=C2
Biological Activity: GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC50 of 0.63 μM. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GPR52 antagonist-1 | 99.86% | GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC50 of 0.63 μM. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.75
HY-N17030Daphnenone -
Similarity Score 0.70
HY-N88261,7-Diphenyl-4-hepten-3-one -
Similarity Score 0.69
HY-134650(4E)-7-(4-Hydroxyphenyl)-1-phenylhept-4-en-3-one -
Similarity Score 0.67
HY-114508Dihydrochalcone -
Similarity Score 0.66
HY-152671hMAO-B-IN-4 -
Similarity Score 0.65
HY-W0123082′-Hydroxydihydrochalcone -
Similarity Score 0.65
HY-N96981,5-Diphenyl-2-penten-1-one -
Similarity Score 0.64
HY-N133643-Hydroxy-1,5-diphenyl-1-pentanone -
Similarity Score 0.64
HY-N17032(S)-3-Hydroxy-1,5-diphenylpentan-1-one -
Explore the MedChemAI to find more analogs
