1245526-82-2
Chemical Structure
Glucocorticoid receptor agonist
- CAS No.: 1245526-82-2
- Formula:C20H20F4N2O2
- Molecular Weight:396.38
IUPAC Name: (R)-2-(4-((1H-pyrrolo[2,3-c]pyridin-2-yl)methyl)-5,5,5-trifluoro-4-hydroxy-2-methylpentan-2-yl)-4-fluorophenol
InChIKey: JFUAWXPBHXKZGA-IBGZPJMESA-N
SMILES: OC1=CC=C(C=C1C(C)(C[C@](O)(C(F)(F)F)CC2=CC3=C(C=NC=C3)N2)C)F
Biological Activity:
Glucocorticoid receptor agonist is a Glucocorticoid receptor agonist that acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin[1].
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Glucocorticoid receptor agonist | 99.06% | Glucocorticoid receptor agonist is a Glucocorticoid receptor agonist that acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin. |
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Keywords
