1246814-55-0
Chemical Structure
Clopidogrel-13C,d3 sulfate
- CAS No.: 1246814-55-0
- Formula:C1513CH15D3ClNO6S2
- Molecular Weight:423.91
IUPAC Name: methyl-13C-d3 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
InChIKey: FDEODCTUSIWGLK-SPZGMPHYSA-N
SMILES: O=S(O)(O)=O.[2H][13C]([2H])([2H])OC(C(C1=C(C=CC=C1)Cl)N2CC3=C(SC=C3)CC2)=O
Biological Activity: Clopidogrel-13C,d3 sulfate is the deuterium and 13C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects[1][2].
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Clopidogrel-13C,d3 sulfate | Clopidogrel-13C,d3 sulfate is the deuterium and 13C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects. | |||||||||||||||||||||
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Clopidogrel-d4 sulfate | Clopidogrel-d4 (sulfate) is the deuterium labeled Clopidogrel sulfate. | |||||||||||||||||||||
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(Rac)-Clopidogrel-d3 sulfate | (Rac)-Clopidogrel-d3 (sulfate) is deuterium labeled Clopidogrel (sulfate). | |||||||||||||||||||||
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(Rac)-Clopidogrel hydrogen-d9 sulfate | (Rac)-Clopidogrel hydrogen-d9 sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects. | |||||||||||||||||||||
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(±)-Clopidogrel bisulfate | 99.39% | (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects. | ||||||||||||||||||||
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References
- [1]. Hagiwara S, et al. Adenosine diphosphate receptor antagonist clopidogrel sulfate attenuates LPS-induced systemic inflammation in a rat model. Shock. 2011 Mar;35(3):289-92. [Content Brief]
- [2]. Liu O, et al. Clopidogrel, a platelet P2Y12 receptor inhibitor, reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. PLoS One. 2012;7(12):e51707. [Content Brief]
