1246817-57-1
Chemical Structure
Hydroxy Bosentan-d6
Synonym(s): Ro 48-5033-d6
- CAS No.: 1246817-57-1
- Formula:C27H23D6N5O7S
- Molecular Weight:573.65
IUPAC Name: N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-(hydroxymethyl)propan-2-yl-1,1,1,3,3,3-d6)benzenesulfonamide
InChIKey: FAJQMBCLPZWTQJ-WFGJKAKNSA-N
SMILES: O=S(NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC3=C(C=CC=C3)OC)(C4=CC=C(C=C4)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])CO)=O
Biological Activity: Hydroxy Bosentan-d6 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].
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Hydroxy Bosentan-d6 | Hydroxy Bosentan-d6 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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Hydroxy Bosentan-d4 | Hydroxy Bosentan-d4 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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Hydroxy bosentan | Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities. | |||||||||||||||||||||
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