125010-17-5
125010-17-5
Chemical Structure
Lignarenone B
- CAS No.: 125010-17-5
- Formula:C15H16O
- Molecular Weight:212.29
IUPAC Name: (3E,5E,7E)-3-methyl-8-phenylocta-3,5,7-trien-2-one
InChIKey: DLEPTASFXXJVDU-XVZDYSDNSA-N
SMILES: CC(/C(C)=C/C=C/C=C/C1=CC=CC=C1)=O
Biological Activity: Lignarenone B is a phenyl conjugated trienone. Lignarenone B can be isolated from the Mediterranean bullomorph Scaphander lignarius. Lignarenone B can inhibit the activity of GSK3β. Lignarenone B can be used in the research of Alzheimer's disease[1][2].
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Lignarenone B | Lignarenone B is a phenyl conjugated trienone. Lignarenone B can be isolated from the Mediterranean bullomorph Scaphander lignarius. Lignarenone B can inhibit the activity of GSK3β. Lignarenone B can be used in the research of Alzheimer's disease. | |||||||||||||||||||||
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References
- [1]. Llorach-Pares L, et al. Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity. Biomolecules. 2020 Apr 21;10(4):639. [Content Brief]
- [2]. Alvarez R, et al. Stereocontrolled Synthesis of Polyenic Ketones from Marine Opisthobranchs[J]. Natural Product Letters, 1995, 6(2): 127-132.
