1253452-78-6
1253452-78-6
Chemical Structure
KS176
- CAS No.: 1253452-78-6
- Formula:C22H19N3O5
- Molecular Weight:405.40
IUPAC Name: N-(4-(2-hydroxyethyl)phenyl)-2-(4-nitrobenzamido)benzamide
InChIKey: LTWQQWSXYYXVGA-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3
Biological Activity: KS176 is a selective BCRP inhibitor (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst assays, respectively). KS176 can be used in the research of cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KS176 | 98.52% | KS176 is a selective BCRP inhibitor (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst assays, respectively). KS176 can be used in the research of cancer. | ||||||||||||||||||||
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References
- [1]. Pick A, et al. Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem. 2010 Sep 3;5(9):1498-505. [Content Brief]
- [2]. Cannon RE, et al. Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier. Toxicol Sci. 2019 Jun 1;169(2):475-484. [Content Brief]
- [3]. Thomas JR, et al. Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier. Fluids Barriers CNS. 2024 Mar 15;21(1):27. [Content Brief]
Keywords
