1253584-63-2
Chemical Structure
Hsp90-IN-17 hydrochloride
- CAS No.: 1253584-63-2
- Formula:C21H21ClN4O7
- Molecular Weight:476.87
IUPAC Name: (S)-2'-amino-7'-methyl-5'H,7'H-spiro[cyclopropane-1,8'-pyrano[4,3-b]pyridin]-5'-one
InChIKey: KYYNVXMTLPAYQC-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C2=C(OC3=CC=C([N+]([O-])=O)C=C3)C=C(O)C=C2O)=C1)NC4CCNCC4.[H]Cl
Biological Activity: Hsp90-IN-17 hydrochloride is a Hsp90 inhibitor. Hsp90-IN-17 hydrochloride binds to the N-terminal ATP-binding pocket of Hsp90, inhibits its chaperone function, and induces the degradation of Hsp90 client proteins. Hsp90-IN-17 hydrochloride inhibits cancer cell proliferation. Hsp90-IN-17 hydrochloride can be used in the research of ovarian cancer[1][2].
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Hsp90-IN-17 hydrochloride | 99.31% | Hsp90-IN-17 hydrochloride is a Hsp90 inhibitor. Hsp90-IN-17 hydrochloride binds to the N-terminal ATP-binding pocket of Hsp90, inhibits its chaperone function, and induces the degradation of Hsp90 client proteins. Hsp90-IN-17 hydrochloride inhibits cancer cell proliferation. Hsp90-IN-17 hydrochloride can be used in the research of ovarian cancer. | ||||||||||||||||||||
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Keywords
