1257868-45-3
1257868-45-3
Chemical Structure
C5aR antagonist-1
- CAS No.: 1257868-45-3
- Formula:C33H35F4N3O2
- Molecular Weight:581.66
IUPAC Name: (2R,3R)-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-N-(4-methyl-3-(trifluoromethyl)phenyl)piperidine-3-carboxamide
InChIKey: PUKBOVABABRILL-VIZCGCQYSA-N
SMILES: C(=O)(N1[C@H]([C@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F
Biological Activity: C5aR antagonist-1 is a potent C5aR antagonist with an IC50 of < 5 nM. C5aR antagonist-1 is applicable to the research of crescentic and necrotizing glomerular lesions[1].
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C5aR antagonist-1 | C5aR antagonist-1 is a potent C5aR antagonist with an IC50 of < 5 nM. C5aR antagonist-1 is applicable to the research of crescentic and necrotizing glomerular lesions. | |||||||||||||||||||||
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