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Cat. No.: HY-183414

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C5aR antagonist-1

C5aR antagonist-1 is a potent C5aR antagonist with an IC₅₀ of < 5 nM. C5aR antagonist-1 is applicable to the research of crescentic and necrotizing glomerular lesions.

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CAS No.: 1257868-45-3
화학식: C₃₃H₃₅F₄N₃O₂
분자량:581.66

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

C5aR antagonist-1 Chemical Structure

CAS No.: 1257868-45-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

C5aR antagonist-1 is a potent C5aR antagonist with an IC₅₀ of < 5 nM. C5aR antagonist-1 is applicable to the research of crescentic and necrotizing glomerular lesions^[1].

In Vitro

C5aR antagonist-1 (Compound 1.148) exhibits potent and highly selective antagonistic activity against C5aR in the ¹²⁵I-C5a competitive binding assay, with an IC₅₀ < 5 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1257868-45-3
분자량 581.66
화학식 C₃₃H₃₅F₄N₃O₂
SMILES

C(=O)(N1[C@H]([C@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Pingchen Fan, et al. C5ar antagonists. WO2011163640A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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