1262041-49-5
1262041-49-5
Chemical Structure
GS-444217
- CAS No.: 1262041-49-5
- Formula:C23H21N7O
- Molecular Weight:411.46
IUPAC Name: 4-(4-cyclopropyl-1H-imidazol-1-yl)-N-(3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl)picolinamide
InChIKey: ZGCMQKWOUIMBEP-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CC(N2C=C(C3CC3)N=C2)=C1)NC4=CC=CC(C5=NN=CN5C6CC6)=C4
Biological Activity: GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM[1].
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GS-444217 | 99.64% | GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM. | ||||||||||||||||||||
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GS-444217 (Standard) | ≥98% | GS-444217 (Standard) is the analytical standard of GS-444217 (HY-100844). This product is intended for research and analytical applications. GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM. | ||||||||||||||||||||
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