127975-78-4
Chemical Structure
FR 75513
- CAS No.: 127975-78-4
- Formula:C19H19NO7
- Molecular Weight:373.36
IUPAC Name: 6-isopropyl 2-methyl 3-hydroxy-5-methyl-2'-nitro-[1,1'-biphenyl]-2,6-dicarboxylate
InChIKey: XSAOKGZBHYQDNI-UHFFFAOYSA-N
SMILES: O=C(C1=C(C=C(C)C(C(OC(C)C)=O)=C1C2=C([N+]([O-])=O)C=CC=C2)O)OC
Biological Activity: FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester series compound that can inhibit the contraction of the detrusor muscle of guinea pig bladder (IC50=3.3 μg/mL). After intravenous injection of FR 75513 into anesthetized rats, it also showed strong inhibitory activity on the detrusor contraction (ID50=0.04 mg/kg).
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FR 75513 | FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester series compound that can inhibit the contraction of the detrusor muscle of guinea pig bladder (IC50=3.3 μg/mL). After intravenous injection of FR 75513 into anesthetized rats, it also showed strong inhibitory activity on the detrusor contraction (ID50=0.04 mg/kg). | |||||||||||||||||||||
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Keywords
