1279829-64-9
1279829-64-9
Chemical Structure
SAR216471 hydrochloride
- CAS No.: 1279829-64-9
- Formula:C28H32Cl2N8O3
- Molecular Weight:599.51
IUPAC Name: N-(6-(4-butyryl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl)-5-chloro-1-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)-1H-indole-3-carboxamide hydrochloride
InChIKey: UQLWHBMSQKUYAI-UHFFFAOYSA-N
SMILES: O=C(C1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(Cl)C=C3)NC4=NN=C(N5N=CC(C(CCC)=O)=C5C)C=C4.Cl
Biological Activity: SAR216471 hydrochloride is a P2Y12 receptor antagonist. SAR216471 hydrochloride has antiplatelet and antithrombotic activities in vivo[1].
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SAR216471 hydrochloride | SAR216471 hydrochloride is a P2Y12 receptor antagonist. SAR216471 hydrochloride has antiplatelet and antithrombotic activities in vivo. | |||||||||||||||||||||
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References
- [1]. Boldron C, et al. N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J Med Chem. 2014 Sep 11;57(17):7293-316. [Content Brief]
Keywords
