128294-71-3
128294-71-3
Chemical Structure
Metallo-β-lactamase-IN-3
- CAS No.: 128294-71-3
- Formula:C10H11NO3S
- Molecular Weight:225.26
IUPAC Name: 4-(3-mercaptopropanamido)benzoic acid
InChIKey: CHPBMGLEWJWPAR-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(NC(CCS)=O)C=C1
Biological Activity: Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1].
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Metallo-β-lactamase-IN-3 | Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7. | |||||||||||||||||||||
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References
Keywords
