128470-16-6
128470-16-6
Chemical Structure
Arbutamine
- CAS. Nr.: 128470-16-6
- Formula:C18H23NO4
- Molecular Weight:317.38
IUPAC Name: (R)-4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)benzene-1,2-diol
InChIKey: IIRWWTKISYTTBL-SFHVURJKSA-N
SMILES: OC1=CC=C([C@@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O
Biological Activity: Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent [1][2][3].
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Arbutamine | 95.0% | Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent . | ||||||||||||||||||||
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References
- [1]. Ruiz M, et al. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m)Tc-sestamibi versus (201)Tl. J Nucl Med. 2002 May;43(5):664-70. [Content Brief]
- [2]. Nagarajan R, et al. A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent. Cardiovasc Drugs Ther. 1996 Mar;10(1):31-8. [Content Brief]
- [3]. Abou-Mohamed G, et, al. Characterization of the adrenergic activity of arbutamine, a novel agent for pharmacological stress testing. Cardiovasc Drugs Ther. 1996 Mar;10(1):39-47. [Content Brief]
