1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Arbutamine

Arbutamine 

Cat. No.: HY-16056 Purity: ≥98.0%
Handling Instructions

Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent .

For research use only. We do not sell to patients.

Arbutamine Chemical Structure

Arbutamine Chemical Structure

CAS No. : 128470-16-6

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1 mg USD 600 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent [1][2][3].

IC50 & Target

β-adrenoceptor[1]

In Vitro

Arbutamine (0.1-100 nM) increases heart contractile force and pD2 value of 8.45. Arbutamine has the affinity constants (KA) value of 7.32 for cardiac β1-adrenergic receptors[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Arbutamine (i.v.; 5, 10, 50, 100, and 250 ng/kg/min) increases mean heart rate, peak positive left ventricular pressure and its first time-derivative, and normal-zone myocardial thickening in 8 open-chest dogs (mean weight, 26.91 kg)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

317.38

Formula

C18H23NO4

CAS No.
SMILES

OC1=CC=C([[email protected]@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: ≥98.0%

References
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Product Name:
Arbutamine
Cat. No.:
HY-16056
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