1289638-16-9
1289638-16-9
Chemical Structure
LDN-193665
- CAS No.: 1289638-16-9
- Formula:C15H11FN4OS
- Molecular Weight:314.34
IUPAC Name: (4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(3-fluorophenyl)methanone
InChIKey: JBTRAENEEJNXFX-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)N=C(NC2=CC=CN=C2)S1)C3=CC(F)=CC=C3
Biological Activity: LDN-193665 is a Tau kinase inhibitor with tauopathy-modifying activity. LDN-193665 inhibits Tau phosphorylation, improves tauopathy in animal models, reduces Sarkosyl-insoluble Tau, and restores memory. It may be necessary to simultaneously target multiple kinases to effectively inhibit tauopathies.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LDN-193665 | LDN-193665 is a Tau kinase inhibitor with tauopathy-modifying activity. LDN-193665 inhibits Tau phosphorylation, improves tauopathy in animal models, reduces Sarkosyl-insoluble Tau, and restores memory. It may be necessary to simultaneously target multiple kinases to effectively inhibit tauopathies. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
