129244-98-0
Chemical Structure
7-Methylsulfinylheptyl isothiocyanate
- CAS No.: 129244-98-0
- Formula:C9H17NOS2
- Molecular Weight:219.37
InChIKey: OGYHCBGORZWBPH-UHFFFAOYSA-N
SMILES: O=S(CCCCCCCN=C=S)C
Biological Activity: 7-Methylsulfinylheptyl isothiocyanate is an activator for MAPK signaling pathway, which downregulates the melanogenesis related proteins and suppresses the melanin synthesis in B16-F1 cells. 7-Methylsulfinylheptyl isothiocyanate induces autophagy. 7-Methylsulfinylheptyl isothiocyanate is an inducer for phase II enzyme, which exhibits chemoprotective effect against carcinogen. 7-Methylsulfinylheptyl isothiocyanate can be used as cosmetic ingredient for skin whitening and anti-inflammation[1][2].
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7-Methylsulfinylheptyl isothiocyanate | 7-Methylsulfinylheptyl isothiocyanate is an activator for MAPK signaling pathway, which downregulates the melanogenesis related proteins and suppresses the melanin synthesis in B16-F1 cells. 7-Methylsulfinylheptyl isothiocyanate induces autophagy. 7-Methylsulfinylheptyl isothiocyanate is an inducer for phase II enzyme, which exhibits chemoprotective effect against carcinogen. 7-Methylsulfinylheptyl isothiocyanate can be used as cosmetic ingredient for skin whitening and anti-inflammation. | |||||||||||||||||||||
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- [1]. Rose P, et al., 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. [Content Brief]
- [2]. Kim AJ, et al., Effect of 7-Methylsulfinylheptyl Isothiocyanate on the Inhibition of Melanogenesis in B16-F1 Cells. Life (Basel). 2021 Feb 20;11(2):162. [Content Brief]
