1292837-95-6
1292837-95-6
Chemical Structure
Tranexamic acid-13C2,15N
Synonym(s): Cyclocapron-13C2,15N
- CAS No.: 1292837-95-6
- Formula:C613C2H1515NO2
- Molecular Weight:160.19
IUPAC Name: (1r,4r)-4-((amino-15N)methyl-13C)cyclohexane-1-carboxylic-13C acid
InChIKey: GYDJEQRTZSCIOI-MWCUNNTJSA-N
SMILES: O[13C]([C@@H]1CC[C@H](CC1)[13CH2][15NH2])=O
Biological Activity: Tranexamic acid-13C2,15N (Cyclocapron-13C2,15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tranexamic acid-13C2,15N | Tranexamic acid-13C2,15N (Cyclocapron-13C2,15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury. | |||||||||||||||||||||
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Tranexamic acid (Standard) | 99.91% | Tranexamic acid (Standard) is the analytical standard of Tranexamic acid. This product is intended for research and analytical applications. Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis . | ||||||||||||||||||||
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Tranexamic acid-13C6 | Tranexamic acid-13C6 (Cyclocapron-13C6) is 13C labeled Tranexamic acid. Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis . | |||||||||||||||||||||
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Tranexamic acid-d2-1 | 98.72% | Tranexamic acid-d2-1 is the deuterium labeled Tranexamic acid. Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. | ||||||||||||||||||||
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Tranexamic acid | 99.88% | Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis. Tranexamic acid is a PROTAC linker. Tranexamic acid is used to synthesize PROTACs (e.g. LZ-07 (HY-172590)). | ||||||||||||||||||||
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References
- [1]. Boström J, et al. Potent fibrinolysis inhibitor discovered by shape and electrostatic complementarity to the drug tranexamic acid. J Med Chem. 2013 Apr 25;56(8):3273-80. [Content Brief]
- [2]. Joshi N, et al. The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury. J Pharmacol Exp Ther. 2014 Jun;349(3):383-92. [Content Brief]
