1303533-81-4
Chemical Structure
Ravidasvir hydrochloride
Synonym(s): PPI-668 hydrochloride
- CAS No.: 1303533-81-4
- Formula:C42H52Cl2N8O6
- Molecular Weight:835.82
IUPAC Name: methyl ((S)-1-((S)-2-(6-(6-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)naphthalen-2-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate dihydrochloride
InChIKey: JYLMWUZJMRNMDA-SPRBZRACSA-N
SMILES: COC(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C2=NC3=CC=C(C4=CC5=C(C=C(C6=CN=C([C@H]7N(CCC7)C([C@H](C(C)C)NC(OC)=O)=O)N6)C=C5)C=C4)C=C3N2)=O)=O.Cl.Cl
Biological Activity: Ravidasvir hydrochloride (PPI-668 hydrochloride) is a pan-genotypic inhibitor for hepatitis C virus (HCV) NS5A protein. Ravidasvir hydrochloride inhibits the replication of HCV, with EC50 of 0.12, 0.01 and 1.14 nM, for HCV gt-1a, gt-1b, and gt-3a replicons, respectively. Ravidasvir hydrochloride exhibits good pharmacokinetic characters in rats[1].
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Ravidasvir hydrochloride | 99.94% | Ravidasvir hydrochloride (PPI-668 hydrochloride) is a pan-genotypic inhibitor for hepatitis C virus (HCV) NS5A protein. Ravidasvir hydrochloride inhibits the replication of HCV, with EC50 of 0.12, 0.01 and 1.14 nM, for HCV gt-1a, gt-1b, and gt-3a replicons, respectively. Ravidasvir hydrochloride exhibits good pharmacokinetic characters in rats. | ||||||||||||||||||||
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Keywords
