Ravidasvir hydrochloride
Based on 1 Customer Validation
Ravidasvir hydrochloride (PPI-668 hydrochloride) is a pan-genotypic inhibitor for hepatitis C virus (HCV) NS5A protein. Ravidasvir hydrochloride inhibits the replication of HCV, with EC50 of 0.12, 0.01 and 1.14 nM, for HCV gt-1a, gt-1b, and gt-3a replicons, respectively. Ravidasvir hydrochloride exhibits good pharmacokinetic characters in rats.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 1303533-81-4
- Formula: C42H52Cl2N8O6
- Molecular Weight:835.82
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 1303533-81-4
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Appearance Solid
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Molecular Weight 835.82
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Formula C42H52Cl2N8O6
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Color White to off-white
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SMILES
COC(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C2=NC3=CC=C(C4=CC5=C(C=C(C6=CN=C([C@H]7N(CCC7)C([C@H](C(C)C)NC(OC)=O)=O)N6)C=C5)C=C4)C=C3N2)=O)=O.Cl.Cl
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Synonyms
PPI-668 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 116.67 mg/mL (139.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1964 mL | 5.9821 mL | 11.9643 mL | 29.9107 mL |
| 5 mM | 0.2393 mL | 1.1964 mL | 2.3929 mL | 5.9821 mL | |
| 10 mM | 0.1196 mL | 0.5982 mL | 1.1964 mL | 2.9911 mL | |
| 15 mM | 0.0798 mL | 0.3988 mL | 0.7976 mL | 1.9940 mL | |
| 20 mM | 0.0598 mL | 0.2991 mL | 0.5982 mL | 1.4955 mL | |
| 25 mM | 0.0479 mL | 0.2393 mL | 0.4786 mL | 1.1964 mL | |
| 30 mM | 0.0399 mL | 0.1994 mL | 0.3988 mL | 0.9970 mL | |
| 40 mM | 0.0299 mL | 0.1496 mL | 0.2991 mL | 0.7478 mL | |
| 50 mM | 0.0239 mL | 0.1196 mL | 0.2393 mL | 0.5982 mL | |
| 60 mM | 0.0199 mL | 0.0997 mL | 0.1994 mL | 0.4985 mL | |
| 80 mM | 0.0150 mL | 0.0748 mL | 0.1496 mL | 0.3739 mL | |
| 100 mM | 0.0120 mL | 0.0598 mL | 0.1196 mL | 0.2991 mL |