1305267-37-1

Roginolisib Chemical Structure
1305267-37-1

Chemical Structure

Roginolisib

Synonym(s): MSC2360844; IOA-244

  • CAS No.: 1305267-37-1
  • Formula:C26H27FN4O5S
  • Molecular Weight:526.58

IUPAC Name: (6-fluoro-1-(4-(morpholinomethyl)phenyl)-5,5-dioxido-1,4-dihydrothiochromeno[4,3-c]pyrazol-3-yl)(morpholino)methanone

InChIKey: NFHSJYKXENYICE-UHFFFAOYSA-N

SMILES: O=C(C1=NN(C2=CC=C(CN3CCOCC3)C=C2)C(C4=CC=CC(F)=C45)=C1CS5(=O)=O)N6CCOCC6

Biological Activity: Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases[1].

Cat. No. Product Name Purity Description Pricing
HY-135827 		Roginolisib 99.66% Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases.
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