1305267-37-1
1305267-37-1
Chemical Structure
Roginolisib
Synonym(s): MSC2360844; IOA-244
- CAS No.: 1305267-37-1
- Formula:C26H27FN4O5S
- Molecular Weight:526.58
IUPAC Name: (6-fluoro-1-(4-(morpholinomethyl)phenyl)-5,5-dioxido-1,4-dihydrothiochromeno[4,3-c]pyrazol-3-yl)(morpholino)methanone
InChIKey: NFHSJYKXENYICE-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(CN3CCOCC3)C=C2)C(C4=CC=CC(F)=C45)=C1CS5(=O)=O)N6CCOCC6
Biological Activity: Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Roginolisib | 99.66% | Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases. | ||||||||||||||||||||
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