13073-35-3
Chemical Structure
L-Ethionine
Synonym(s): L-ETH
- CAS No.: 13073-35-3
- Formula:C6H13NO2S
- Molecular Weight:163.24
IUPAC Name: S-ethyl-L-homocysteine
InChIKey: GGLZPLKKBSSKCX-YFKPBYRVSA-N
SMILES: CCSCC[C@H](N)C(O)=O
Biological Activity: L-Ethionine (L-ETH) is an amino acid derivative. L-Ethionine serves as a substrate for ATP:L-methionine S-adenosyltransferase, which targets its L-stereoisomer. L-Ethionine blocks the synthesis of N6-dimethyladenosine in rat liver tRNA/4S RNA via its major hepatic metabolite S-adenosylethionine, inducing methyl-deficient rat liver tRNA/4S RNA. L-Ethionine can be used in studies of liver cancer and hepatocarcinogenesis mechanisms[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Ethionine | 99.66% | L-Ethionine (L-ETH) is an amino acid derivative. L-Ethionine serves as a substrate for ATP:L-methionine S-adenosyltransferase, which targets its L-stereoisomer. L-Ethionine blocks the synthesis of N6-dimethyladenosine in rat liver tRNA/4S RNA via its major hepatic metabolite S-adenosylethionine, inducing methyl-deficient rat liver tRNA/4S RNA. L-Ethionine can be used in studies of liver cancer and hepatocarcinogenesis mechanisms. | ||||||||||||||||||||
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References
- [1]. Friedman MA, et al. Acute lethality of D- and L-ethionine in Swiss mice. Cancer letters. 1977 Jul;3(1-2):71-6.
- [2]. van der Meer JW, et al. Abstract!. The Netherlands journal of medicine. 2002 Dec;60(11):418. [Content Brief]
- [3]. Mifflin RC, et al. Genetic analysis of L-ethionine-mediated induction of alpha-fetoprotein in mice. Somatic cell and molecular genetics. 1988 Nov;14(6):553-66.
